麻醉诱导时联合应用右旋美托咪啶在胸腰椎骨折手术中的效果

doi:10.3969/j.issn.2097-0005.2021.06.013

betway必威登陆网址（betway.com ）学报 ›› 2021, Vol. 42 ›› Issue (6): 445-447.DOI: 10.3969/j.issn.2097-0005.2021.06.013

麻醉诱导时联合应用右旋美托咪啶在胸腰椎骨折手术中的效果

孙素花

成武县人民医院,山东成武 274200

收稿日期:2020-12-10 出版日期:2021-06-25 发布日期:2021-08-25
作者简介:孙素花(1980—),女,山东成武人,主治医师,硕士,主要从事麻醉药理与围术期器官保护工作。E-mail:zhuwenjing999888@163.com。
基金资助:
菏泽医学专科学校附属医院科研项目(HYFY202024)。

Clinical effect of anesthesia induction combined with dexmedetomidine in thoracolumbar fracture surgery

Sun Suhua

Chengwu People's Hospital,Heze 274200,China

Received:2020-12-10 Online:2021-06-25 Published:2021-08-25

摘要/Abstract

摘要： 目的研究分析麻醉诱导时联合应用右旋美托咪啶在胸腰椎骨折手术中的临床效果。方法将成武县人民医院于2019年6月—2020年6月接收的106例胸腰椎骨折手术患者随机分为常规组(生理盐水)、研究组(右旋美托咪啶),各53例。研究组在常规麻醉的基础上加用右旋美托咪啶,观察患者的苏醒时间、拔管时间、血压、心率变化等,重点观察其对患者围拔管期血流动力学、苏醒过程的影响。结果研究组T₂时的血压高于T₀时,心率低于T₀时,差异有统计学意义(P<0.05),但两组血压、心率差异无统计学意义(P>0.05)。研究组苏醒时间、拔管时间更长,躁动评分更低,与常规组差异有统计学意义(P<0.05)。右旋美托咪啶应用量与心率、血压并无相关性,但是与拔管时间、苏醒时间呈正相关,与躁动评分呈负相关。结论对于实施全身麻醉的胸腰椎骨折患者而言,右旋美托咪啶可帮助患者较好地稳定围拔管期血压、心率,促使其苏醒过程改善,效果优良,值得引起临床重视并大范围应用。

关键词: 右旋美托咪啶, 胸腰椎骨折手术, 全身麻醉, 血流动力学, 苏醒时间

Abstract: Objective: To study and analyze the clinical effect of anesthesia induction combined with dexmedetomidine in thoracolumbar fracture surgery, focusing on the effect on hemodynamics and recovery process of patients during periextubation. Methods: 106 cases of thoracolumbar fracture surgery patients received by the department of orthopedics in our hospital from June 2019 to June 2020 were randomly divided into routine group (normal saline) and study group (dextromethorhomidine), 53 cases each.In the study group, Dexmedetomidine was added on the basis of general anesthesia to observe the time of recovery, extubation time, blood pressure, heart rate changes, etc. Results: When the blood pressure at T₂ was higher than T₀, the heart rate was lower than T₀ (P＜0.05), but there was no difference in blood pressure and heart rate between the two groups (P＞0.05).The study group had a significantly lower score for restlessness and longer wake time and extubation time than the control group (P＜0.05).The dosage of dextrometomidine was not correlated with heart rate and blood pressure, but positively correlated with extubation time and wake time, and negatively correlated with agitation score. Conclusion: For thoracolumbar fracture patients under general anesthesia, dextromethorax can help patients stabilize their blood pressure and heart rate during peritubal extubation and improve their resuscitation process. It has a good effect and is worthy of clinical attention and wide application.

Key words: dextrometomidine, thoracolumbar fracture surgery, general anesthesia, hemodynamics, wake up of time

中图分类号:

R614

孙素花. 麻醉诱导时联合应用右旋美托咪啶在胸腰椎骨折手术中的效果[J]. betway必威登陆网址（betway.com ）学报, 2021, 42(6): 445-447.

Sun Suhua. Clinical effect of anesthesia induction combined with dexmedetomidine in thoracolumbar fracture surgery[J]. Journal of Shandong First Medical Unversity & Shandong Academy of Medical Sciences, 2021, 42(6): 445-447.

参考文献

[1] 李俊威.右旋美托咪啶对胸腰椎骨折全身麻醉患者的应用效果及血流动力学情况影响评价[J].北方药学,2020,17(04):60-61.
[2] 郑文婧,郄晓娟,郑文芳,等.右美托咪定对老年颈动脉狭窄患者胸腰椎骨折全麻过程中血流动力学及术后认知功能的影响[J].中国老年学杂志,2019,39(20):4999-5002.
[3] 侯俊芳.右美托咪定对脊柱骨折手术全身麻醉患者围拔管期血流动力学及苏醒过程的影响[J].中国当代医药,2019,26(18):123-126.
[4] 徐义国,吴祥,李红宝,等.右美托咪定辅助全身麻醉对老年股骨颈骨折患者血清T淋巴细胞亚群水平的影响[J].中国医药导报,2019,16(18):154-158.
[5] 肖荣,来伟,鲁利峰,等.不同浓度的右美托咪定对老年腰椎术患者的镇静效果、氧化应激和血流动力学的影响[J].现代生物医学进展,2018,18(22):4312-4316.
[6] 朱亮亮.盐酸右美托咪定对多发性骨折患者术中血流动力学的影响[J].湖北科技学院学报(医学版),2018,32(04):341-344.
[7] 肖宝连.对行全麻手术的胸腰椎骨折患者采用不同剂量的右美托咪定进行辅助麻醉的效果评析[J].当代医药论丛,2018,16(08):90-91.
[8] 于国军,陈文超,袁哲.盐酸右美托咪定对多发性骨折术中血流动力学的影响[J].贵州医科大学学报,2018,43(02):244-248.
[9] 黄浩铭.右美托咪定对老年骨折手术患者全身麻醉苏醒期躁动的影响[J].世界最新医学信息文摘,2017,17(A4):126-127.
[10] 吴卫强,刘聪霞,李华平,等.右旋美托咪啶在胸腰椎骨折手术中的应用价值[J].中国临床医生杂志,2017,45(06):92-95.
[11] 周艳.右旋美托咪定对胸腰椎骨折全身麻醉患者围拔管期血流动力学的影响[J].医学理论与实践,2017,30(24):3673-3674.
[12] 刘华斌.右旋美托咪定对胸腰椎骨折全身麻醉患者围拔管期血流动力学的影响研究[J].药品评价,2017,14(12):42-44.
[14] 杨宁,贾其余.两种方法治疗胸腰椎骨折的疗效比较[J].临床骨科杂志,2020,23(06):769-773.
[15] 覃远浩.右旋美托咪啶对神经阻滞麻醉在下肢骨折手术中止血带耐受及血流动力学相关指标的影响[J].世界最新医学信息文摘,2019,19(02):127-128.
[16] 李元春.右旋美托咪定辅助颈丛神经阻滞用于锁骨骨折手术的临床疗效观察[J].中国社区医师,2018,34(17):45-46.
[17] 项绪强.盐酸右美托咪定对全麻患者麻醉用药量及麻醉恢复期的影响[J].临床合理用药杂志,2020,13(35):62-63.

麻醉诱导时联合应用右旋美托咪啶在胸腰椎骨折手术中的效果

Clinical effect of anesthesia induction combined with dexmedetomidine in thoracolumbar fracture surgery

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