国际肿瘤学杂志

国际肿瘤学杂志››2011,Vol. 38››Issue (12): 923-926.

• 综述 •上一篇下一篇

食管癌治疗敏感基因单核苷酸多态性

季文豪, 凌志强, 毛伟敏

  1. 310022杭州，浙江省肿瘤医院浙江省肿瘤研究所
  • 出版日期:2011-12-08发布日期:2011-11-25
  • 通讯作者:凌志强，E-mail:lingzq@hotmail.com E-mail:lingzq@hotmail.com
  • 基金资助:

    浙江省自然科学基金资助项目Y2080749

Therapeutic sensitivity gene SNP in esophageal cancer

JI Wen-Hao, LING Zhi-Qiang, MAO Wei-Min

  1. Zhejiang Cancer Research Institute, Zhejiang Province Cancer Hospital , 310022 Hangzhou , China
  • Online:2011-12-08Published:2011-11-25

PDF

1687

被引次数

2

摘要：研究显示食管癌治疗过程中表现的个体差异与遗传多态性有密切关系。已证实顺铂及5氟尿嘧啶（5-FU）代谢相关基因、凋亡及血管生成相关基因单核苷酸多态性与食管癌治疗敏感性密切相关。

Abstract:Genetic polymorphisms are thought to be associated with this difference.A large number of evidences show that 5-FU and cisplatin metabolism 、apoptosis and angiogenesis related gene SNPs are associated with esophageal cancer's therapeutic sensitivity.