关键词:诊断技术和方法,活组织检查,颈部淋巴结病变

Abstract:Objective To evaluate the clinical application value of pathological diagnosis by using the ultrasound-guided percutaneous needle core biopsy (PNCB) for cervical lymph lesions. Methods Two hundred and ten patients with cervical lymph lesions underwent ultrasound-guided PNCB, and pathological diagnosis were made based on core biopsy material. The results of study were concluded by comparing the pathological diagnosis from core biopsy of the lymph nodes with those from excision biopsy. Results There were 210 patients underwent ultrasound- guided PNCB, 98.6%(207/210) cases of core biopsies yielded adequate material at first time and 92.9% (195/210) cases of those had pathologic diagnosis. The accuracy of ultrasound-guided PNCB in differentiating benign from malignant lymphadenopathy were 99.4%. The diagnostic accuracy of metastatic tumor and lymphoma by ultrasound-guided PNCB was 96.4% and 86.1%, respectively. Only 67.7% patients with lymphoma can be classified by ultrasound-guided PNCB. Conclusion Ultrasound-guided PNCB in patients with neck lymph lesions is a safe, convenient and quick procedure that has a high diagnosis accuracy. Ultrasound- guided PNCB can replace the open surgery for neck lymph node diagnostic method. Due to the complicated and diverse pathologic performance, lymphoma should be cut by open surgery to confirm the diagnosis and classification.