Journal of International Oncology››2017,Vol. 44››Issue (11): 866-868.doi:10.3760/cma.j.issn.1673-422X.2017.11.016

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MicroRNA and Helicobacter pylori-associated gastric carcinoma

Li Chunxia, Wang Xuehong

  1. Graduate School of Qinghai University, Xining 810000, China
  • Received:2017-08-28Online:2017-11-08Published:2017-11-24
  • Contact:Wang Xuehong E-mail:lindawang0710@hotmail.com

Abstract:Helicobacter pylori infection can cause a series of microRNAs (miRNAs) disorders. These abnormal expressions of miRNAs can participate in the genesis and development of Helicobacter pyloriassociated gastric carcinoma through regulating cell proliferation, differentiation and apoptosis. Identifying the targets and regulatory pathways of various miRNAs in the development of Helicobacter pyloriassociated gastric cancer will provide a new direction for early diagnosis, prognosis and individualized treatment of gastric cancer.

Key words:MicroRNAs,Gastric neoplasms,Helicobacter pylori