Journal of International Oncology››2012,Vol. 39››Issue (2): 148-151.

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Vascular endothelial growth factor and renal cell carcinoma

ZHOU Shu-Kui, WANG Shun-Ping, WANG Yue-Min

  1. Department ofUrology ,EastHospital,Tongji University,Shanghai 200120,China
  • Online:2012-02-08Published:2012-01-18
  • Contact:Corresponding author: Wang Yue-min, E-mail: wangyuemin@hotmail.com E-mail:wangyuemin@hotmail.com

Abstract:Vascular endothelial growth factor(VEGF)is high expression in the organization of renal cell carcinoma and mainly regulate by VHL gene and hypoxic of organization. Moreover, it can be a biomarker to judge renal cell carcinoma tumor progression and prognostic. In recent years,anti-VEGF targeted drugs are used for the treatment of renal cell carcinoma and receive meaningful clinical benefits.