Journal of International Oncology››2012,Vol. 39››Issue (8): 658-661.

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YIN Bao-Hui, JIA Xiu-Hong

  1. Department of Pediatrics, the Affiliated Hospital of Binzhou Medical University, Binzhou 256603, China
  • Online:2012-09-22Published:2012-09-24
  • Contact:JIA Xiu-hong, E-mail:jiaxiuhong001@163.com E-mail:jiaxiuhong001@163.com

Abstract:The caudal-type homeobox gene is a member of homeobox gene—Para-HOX family, including CDX1,CDX2 and CDX4. As a transcriptional factor, CDX plays an important role in embryo development, hematopoietic system formation, intestinal epithelium tissue development and so forth. The abnormal expression of CDX is usually closely related with tumorigenesis. Researching the relationship between CDX and tumors will contribute to tumor diagnosis and treatment.

Key words:Genes,homeobox,Neoplasms