Journal of International Oncology››2012,Vol. 39››Issue (11): 803-805.

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Biological function of long non-coding RNAs in human malignant neoplasms

LIU Chang, JIAO Yang

  1. Key laboratory of Radiation Oncology of Suzhou, Jiangsu Province Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou 215123, China
  • Online:2012-11-08Published:2012-11-16

Abstract:Long non-coding RNAs(LncRNAs) refer to such a kind of RNAs which possess none or very few open reading frames, thus could only encode none or little protein. Recent studies suggest that LncRNAs tissue- specially expressed in several human cancers,and might play a key role in the diagnosis and prognostic of these malignant neoplasms.

Key words:Neoplasms,Neoplasms metastasis,Diagnosis,Prognostic,Long non-coding RNA