Journal of International Oncology››2012,Vol. 39››Issue (11): 840-843.

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Applications of nucleic acid aptamers in cancer diagnosis and treatment

LI Ye, CAO Hong-Yong, YUAN Ai-Hua, MIAO Yi

  1. Department of General Surgery, The Nanjing First Hospital and The People’s Hospital of Jiangsu Province Affiliated to Nanjing Medical University, Nanjing 210006,China
  • Online:2012-11-08Published:2012-11-16
  • Contact:Corresponding author: CAO Hong-yong , E-mail: caohongy6167@163.com E-mail:caohongy6167@163.com

Abstract:Due to their small molecular weight, strong penetrating power, wide target range, strong ability of binding targets, stable quality, little immunogenicity, easiness to be synthesized and modified, and functional roles in molecular recognition and signal transduction, nucleic acid aptamers are now used as tools for molecular recognition and drugs delivery for the diagnosis and treatment of many diseases.

Key words:Neoplasms,Molecular diagnostic techniques,Therapy,Nucleic acid aptamer