Journal of International Oncology››2013,Vol. 40››Issue (3): 200-202.

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Breast cancer and thyroid diseases

WEN Fen,ZHU Li-Ping

  1. Department of Breast Surgery,the Affiliated Cancer Hospital of Xinjiang Medical University ,Urumchi 830011, China

  • Online:2013-03-08Published:2013-02-25
  • Contact:ZHU Li-ping, E-mail: zlp_1005@sina.com E-mail:zlp_1005@sina.com

Abstract:Thyroid hormones and the related antibodies have some function in the natural process of breast cancer development. The possible mechanisms include: iodine complex can inhibit breast cell proliferation and can induce apoptosis; thyroid hormone can affect breast cancer cell proliferation and apoptosis; the imbalance of thyroid hormone and estrogen hormone promotes breast cells cancerous; hypothyroidism may affect the proliferation and invasiveness of breast tumors; lymphocytic infiltration or abnormal local immune response in thyroid disease.

Key words:Breast neoplasms,Thyroid neoplasms,Thyroid hormones