Abstract:As a noncoding singlestrand small RNA, microRNA (miRNA) plays an important role in posttranslational regulation. Its role in tumor formation has become a study hotspot. A large body of studies indicate that the abnormal expression of miRNA involves in the occurrence and development of liver cancer, which can be used for the diagnosis, therapy and prognosis evaluation of liver cancer. Indepth exploration of the molecular mechanism of miRNA and the relationship between miRNA and liver cancer could provide novel ideas and methods for the therapy and prevention of liver cancer.

Key words:Liver neoplasms,MicroRNAs,Therapy