Role of zincfinger protein X-linked in the development of neoplasms

Abstract

YAN Lei-Lei, PENG Jia-Yuan, WANG Yu. Role of zincfinger protein X-linked in the development of neoplasms[J]. Journal of International Oncology, 2014, 41(12): 890-893.

［1］ Miller J, McLachlan AD, Klug A. Repetitive zincbinding domains in the protein transcription factor IIIA from Xenopus oocytes［J］. EMBO J, 1985, 4(6): 16091614. ［2］ Hoovers JM, Mannens M, John R, et al. Highresolution localization of 69 potential human zinc finger protein genes: a number are clustered［J］. Genomics, 1992, 12(2): 254263. ［3］ Chandrasekharan S, Kumar S, Valley CM, et al. Proprietary science, open science and the role of patent disclosure: the case of zincfinger proteins［J］. Nat biotechnol, 2009, 27(2): 140144. ［4］ Schnidar H, Eberl M, Klingler S, et al. Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway［J］. Cancer Res, 2009, 69(4): 12841292. ［5］ Poloumienko A. Cloning and comparative analysis of the bovine, porcine, and equine sex chromosome genes ZFX and ZFY［J］. Genome, 2004, 47(1): 7483. ［6］ SchneiderGdicke A, BeerRomero P, Brown LG, et al. Putative transcription activator with alternative isoforms encoded by human ZFX gene［J］. Nature, 1989, 342(6250): 708711. ［7］ Fortunel NO, Otu HH, Ng HH, et al. Comment on " ′Stemness′: transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature"［J］. Science, 2003, 302(5644): 393393. ［8］ Huang D, Gao Q, Guo L, et al. Isolation and identification of cancer stemlike cells in esophageal carcinoma cell lines［J］. Stem Cells Dev, 2009, 18(3): 465474. ［9］ RamalhoSantos M, Yoon S, Matsuzaki Y, et al. "Stemness": transcriptional profiling of embryonic and adult stem cells［J］. Science, 2002, 298(5593): 597600. ［10］ GalanCaridad JM, Harel S, Arenzana TL, et al. Zfx controls the selfrenewal of embryonic and hematopoietic stem cells［J］. Cell, 2007, 129(2): 345357. ［11］ Ivanova N, Dobrin R, Lu R, et al. Dissecting selfrenewal in stem cells with RNA interference［J］. Nature, 2006, 442(7102): 533538. ［12］ Zhou Y, Su Z, Huang Y,et al. The Zfx gene is expressed in human gliomas and is important in the proliferation and apoptosis of the human malignant glioma cell line U251［J］. J Exp Clin Cancer Res, 2011, 30: 114. ［13］ Zhu Z, Li K, Xu D, et al. ZFX regulates glioma cell proliferation and survival in vitro and in vivo［J］. J Neurooncol, 2013, 112(1): 1725. ［14］ Wang J, Wang H, Li Z, et al. cMyc is required for maintenance of glioma cancer stem cells［J］. PLoS One, 2008, 3(11): e3769. ［15］ Hendruschk S, Wiedemuth R, Aigner A, et al. RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo［J］. Neuro Oncol, 2011, 13(10): 10741089. ［16］ Komata T, Kanzawa T, Takeuchi H, et al. Antitumour effect of cyclindependent kinase inhibitors (p16INK4A, p18INK4C, p19INK4D, p21WAF1/CIP1 and p27KIP1) on malignant glioma cells［J］. Br J Cancer, 2003, 88(8): 12771280. ［17］ Fang X, Huang Z, Zhou W, et al. The zinc finger transcription factor ZFX is required for maintaining the tumorigenic potential of glioblastoma stem cells［J］. Stem Cells, 2014, 32(8): 20332047. ［18］ Zheng H, Ying H, Yan H, et al. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation［J］. Nature, 2008, 455(7216): 11291133. ［19］ Radke J, Bortolussi G, Pagenstecher A. Akt and cMyc induce stemcell markers in mature primary p53-/- astrocytes and render these cells gliomagenic in the brain of immunocompetent mice［J］. PloS one, 2013, 8(2): e56691. ［20］ Li K, Zhu ZC, Liu YJ, et al. ZFX knockdown inhibits growth and migration of nonsmall cell lung carcinoma cell line H1299［J］. Int J Exp Pathol, 2013, 6(11): 24602467. ［21］ Namls HM, MezaZepeda LA, Bary T, et al. Modulation of the osteosarcoma expression phenotype by microRNAs［J］. PLoS One, 2012, 7(10): e48086. ［22］ Guled M, Lahti L, Lindholm PM, et al. CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant mesothelioma  A miRNA microarray analysis［J］. Genes Chromosomes Cancer, 2009, 48(7): 615623. ［23］ Zha W, Cao L, Shen Y, et al. Roles of Mir144ZFX Pathway in Growth Regulation of NonSmallCell Lung Cancer［J］. PLoS One, 2013, 8(9): e74175. ［24］ Akiyoshi S, Fukagawa T, Ueo H, et al. Clinical significance of miR144ZFX axis in disseminated tumour cells in bone marrow in gastric cancer cases［J］. Br J Cancer, 2012, 107(8): 13451353. ［25］ Wu S, Lao XY, Sun TT, et al. Knockdown of ZFX inhibits gastric cancer cell growth in vitro and in vivo downregulating the ERKMAPK pathway［J］. Cancer Lett, 2013, 337(2): 293300. ［26］ Lai KP, Chen J, He M, et al. Overexpression of ZFX confers selfrenewal and chemoresistance properties in hepatocellular carcinoma［J］. Int J Cancer, 2014, 135(8): 17901799.

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Role of zincfinger protein X-linked in the development of neoplasms

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