Abstract:Whole brain radiation therapy has become the standard treatment of nonsmall cell lung cancer (NSCLC) with brain metastasis, because it prolongs the survival times of NSCLC patients with brain metastases. The emergence of molecular targeted drugs is a major innovation in the traditional sense of the cancer treatment. Molecular targeted drugs have many advantages such as convenient dosing, rapid onset, improving the intracranial and extracranial tumor lesions at the same time, mild adverse reactions and good tolerance, which provide a new and better choice for the treatment of NSCLC patients with brain metastases.

Key words:Carcinoma, non-small-cell lung,Neoplasm metastasis,Radiotherapy,Targeted therapy