%A Wang Yanjun, Jiang Yongxin, Liu Shan, Wang Hong, Ge Lyu %T Radiosensitization of artemisinin and its derivatives in tumors %0 Journal Article %D 2016 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2016.08.012 %P 612-614 %V 43 %N 8 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_10025.shtml} %8 2016-08-08 %X Artemisinin and its derivative is a kind of efficient, quick and low toxicity of antimalarial drug. In recent years, we find that artemisinin drugs can not only against malaria, but also have pharmacological effects of immunosuppression, antiviral and anticancer. A number of studies have confirmed that artemisinin and its derivatives have the radiosensitization effects in nasopharyngeal carcinoma, cervical cancer, lung cancer and glioma, and their mechanisms are related to decreasing Wee1 protein expression, increasing Cyclin B1 protein expression, blocking G2M phase and cell apoptosis.