%A Zhang Zijin, Ai Bin %T Advances of immune checkpoint blockades in the treatment of digestive cancers %0 Journal Article %D 2017 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2017.01.017 %P 63-66 %V 44 %N 1 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_10134.shtml} %8 2017-01-08 %X Immune checkpoint blockade is a hot spot in treatment of cancers recently, and their efficacy in digestive cancer cannot been ignored. Nivolumab is superior to sorafenib in the terms of prolonging survival period for the patients with advanced live cancer. The effective rate of Pembrolizumab for advanced PD-L1 positive expression esophageal cancer can reach 30%. Nevertheless, Ipilumumab shows no significant efficacy in advanced pancreatic carcinoma. More researches are on the way, such as Avelumab in advanced gastric cancer, and Pembrolizumab in advanced esophageal squamous carcinoma.