%A Lin Lin, Zhou Juying %T Molecular mechanism of G2 phase cell cycle arrest in tumor cellsLin Lin*, Zhou Juying. *Department of Radiation Oncology, First Affiliated Hospital of Soochow University, Suzhou 215000, China %0 Journal Article %D 2017 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673422X.2017.03.007 %P 186-189 %V 44 %N 3 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_10172.shtml} %8 2017-03-08 %X The formation and progression of tumor is inseparable from the changes of cell cycle regulatory proteins. The G2M period block effect of tumor cells is especially important in slowing the growth of tumor and improving the curative effect. DNA damage receptor, signal transduction factor and effectors are the classical pathways to mediate G2 phase arrest of tumor cells, and have the potential to be new targets for tumor therapy.