%A Zhu Qiumei, Zhang Yong %T Research progress of Dickkopf1 related tumor metastasis %0 Journal Article %D 2017 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2017.06.010 %P 442- %V 44 %N 6 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_10228.shtml} %8 2017-06-08 %X As a secreted glycoprotein, Dickkopf1 (DKK1) is closely related to tumor metastasis, and it is highly or lowly expressed in tumor. The high expression of DKK1 promotes the metastasis of a variety of malignant tumors including liver cancer, gastric cancer, nonsmall cell lung cancer and breast cancer. Recent studies have found that DKK1 is inextricably bound up with the latent metastasis of tumor.