%A Zhang Huibo, Yang yanying, Song Qibin %T Association between MTHFR polymorphisms and colorectal cancer %0 Journal Article %D 2017 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2017.08.016 %P 619-621 %V 44 %N 8 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_10291.shtml} %8 2017-08-08 %X Colorectal cancer (CRC) is one of the most common malignancies in the world. Methylene tetrahydrofolate reductase (MTHFR) is a key enzyme of folate metabolism process. In recent years, many studies indicate that MTHFR polymorphisms are significantly associated with the morbidity, response to chemotherapy and prognosis of CRC, but conclusions are inconsistent and remain to be further confirmed.