%A WU Xin, QU Xiu-Juan, ZHANG Ling-Yun %T Antitumor therapy of thalidomide %0 Journal Article %D 2018 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673422X.2018.08.009 %P 490-493 %V 45 %N 8 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_10503.shtml} %8 2018-08-08 %X Studies have found that thalidomide has antitumor activity due to its inhibitory effect on angiogenesis and immunomodulation, which has been effectively used in targeted therapy resistant nonsmall cell lung cancer, castrationresistant prostate cancer, colorectal cancer, advanced hepatocarcinoma and advanced gastric cancer. Many clinical studies have also found that it has certain practical value in the aspects of improvement of cancer cachexia and chemotherapyinduced nausea and vomiting.