%A Zhong Chenyi, Mao Yundong %T Regulating effect of lncRNA on aerobic glycolysis in tumor cells %0 Journal Article %D 2019 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2019.03.008 %P 170-173 %V 46 %N 3 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_10608.shtml} %8 2019-03-08 %X Long noncoding RNA (lncRNA) is a kind of RNA with a length greater than 200 nucleotides and lacks proteincoding function. Varieties of lncRNAs have been found to play major roles in the aerobic glycolysis of tumor cells, such as lncRNAp21, H19, prostate specific transcript 1 (PGCEM1) and so on. In tumor cells, lncRNA can directly regulate the ratelimiting enzyme in the glycolytic pathway, also can indirectly regulate the glycolysis by hypoxia inducible factor1α (HIF1α) or protooncogene cmyc. Further study on the mechanism of lncRNA regulating tumor cell glycolysis is expected to open up new ideas for the diagnosis and treatment of tumor diseases.