%A Zhou Qifen, Wu Chunlin %T Effect of ubiquitin-specific protease on radiosensitivity of tumor %0 Journal Article %D 2019 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2019.07.006 %P 420-422 %V 46 %N 7 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_10668.shtml} %8 2019-07-08 %X Ubiquitin-specific protease is a member of the deubiquitinating enzyme family, which can reverse the ubiquitination of proteins and stabilize proteins. It affects radiosensitivity of tumor by regulating DNA damage, cell cycle, nuclear factor-κB signaling pathway, Nrf2-Keap1 signaling pathway and oncogene c-myc. It is expected to become a new target for tumor radiotherapy sensitization.