%A Zhou Jiamin, Ye Lisha, Wang Guohua %T Roles of microRNA in the regulation of tumor-associated macrophage polarization during the remodeling of breast cancer immune microenvironment %0 Journal Article %D 2020 %J Journal of International Oncology %R 10.3760/cma.j.cn371439-20200401-00050 %P 428-430 %V 47 %N 7 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_10833.shtml} %8 2020-07-08 %X

Tumor associated macrophage (TAM), as the main type of immune cells in tumor microenvironment, becomes an active participant in the development of breast cancer. MicroRNA (miRNA) can regulate post-transcriptional gene expression, modulation of macrophage function by affecting its polarization typing and transformation, and ultimately contribute to the occurrence and development of breast cancer. It could provide a new diagnosis and clinical treatment strategy for the treatment of breast cancer by summarizing the mechanisms of miRNA in the polarization of TAM.