Tumor-associated inflammation is closely related to the development of tumors. The ratio of lymphocytes to C-reactive protein (LCR) is a new marker reflecting the inflammatory state of the body, which plays an important role in predicting the prognosis of digestive system neoplasms. Compared with the detection of lymphocytes or C-reactive protein alone, this marker has higher sensitivity and accuracy, and can provide a new direction for clinical diagnosis and treatment of digestive system neoplasms.