Esophageal carcinoma is at a high incidence in Shandong province，and there are many non-standard aspects in the current diagnosis and treatment. The standardized diagnosis and treatment of multiple disciplines，including medical oncology，surgical oncology，radiotherapy，imaging，endoscopy，pathology，etc.，is crucial to improve local control，overall survival rate，and quality of life. This guideline is hereby formulated based on clinical needs and combined with the progress of multidisciplinary diagnosis and treatment in recent years.