%A Li Jinge, Li Jing, Zhang Zhenhan, Guo Jianxin, Wang Jingpu, Wu Zhongbing %T Research progress of 4-nitroquinoline-1-oxide-induced esophageal squamous cell carcinoma model in mice %0 Journal Article %D 2023 %J Journal of International Oncology %R 10.3760/cma.j.cn371439-20230227-00084 %P 437-441 %V 50 %N 7 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_11320.shtml} %8 2023-07-08 %X

Esophageal squamous cell carcinoma （ESCC） is one of the most common malignant tumors with a poor prognosis. 4-nitroquinoline-1-oxide （4NQO） is a water-soluble quinoline derivative that can successfully induce the production of squamous cell carcinomain vivo. Establishing and optimizing experimental methods for 4NQO induced ESCC formation in mice can provide a more suitablein situmodel for the study of ESCC.