%A Gong Yan, Chen Honglei %T Research progress on the mechanism of microRNA regulation of cisplatin resistance in ovarian cancer %0 Journal Article %D 2024 %J Journal of International Oncology %R 10.3760/cma.j.cn371439-20231109-00030 %P 186-190 %V 51 %N 3 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_11418.shtml} %8 2024-03-08 %X

Cisplatin resistance is an important factor in the poor treatment effect of ovarian cancer patients. MicroRNA （miRNA） can regulate cellular structural molecules， DNA repair， cell cycle， apoptosis and Wnt/β-catenin signaling pathway， autophagy， methylation and cancer stem cell， which are involved in the regulation of cisplatin resistance in ovarian cancer. Further understanding the mechanism of miRNA regulation of cisplatin resistance in ovarian cancer will help find new treatment options to optimize existing treatment plans and improve efficacy.