%A WEI Yu-Ping, DONG Liang, BI Wen-Xiang %T Effects of insulinoma-glucagonoma clone 20 isoforms on cancer cells %0 Journal Article %D 2011 %J Journal of International Oncology %R %P 816-818 %V 38 %N 11 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_8618.shtml} %8 2011-11-08 %X Insulinoma-glucagonoma clone 20 can express at least 6 isoforms in human cells. These isoforms can affect cell apoptosis and proliferation through apoptosis related signaling pathway, such as TRAIL or TNF signaling pathways. Furthermore, insulinoma-glucagonoma clone 20, as a GTP-GDP exchange factor, participates in the transportation of nerve synaptophysins.