%A SUN Shou-Liang, QIAN Jun %T Pim-3 gene and its related effect %0 Journal Article %D 2012 %J Journal of International Oncology %R %P 105-107 %V 39 %N 2 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_8695.shtml} %8 2012-02-08 %X Pim-3, a new member of the the proto-oncogene pim family which expresses serine and threonine kinase activity, shows a high similar to pim-1 and pim-2 at the function, structure and sequence. Pim-3 plays an important regulative role in the cell cycle transform, cell apoptosis and occurrence of the malignant tumors by phosphorylating numerous specific substrates.