%A WANG Hong-Mei, XU Jun-Fa %T Advances of tumor-associated fibroblasts in carcinogenesis %0 Journal Article %D 2012 %J Journal of International Oncology %R %P 163-166 %V 39 %N 3 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_8713.shtml} %8 2012-03-08 %X Stromal cell types of the neoplastic microenvironment play important roles in the occurrence and development of tumor. Tumor-associated fibroblasts(TAFs) are the most abundant cells in tumor stroma.They promote the malignant transformation of epithelial cells and other cells through cell-cell communication via various soluble factors.