%A WU Fen-Ping, YANG Zhi-Xiong %T Correlation between lysyl oxidase-like protein 2 and neoplasms and its mechanism%0 Journal Article %D 2012 %J Journal of International Oncology %R %P 246-248 %V 39 %N 4 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_8752.shtml} %8 2012-04-08 %X Lysyl oxidase-like protein 2 (LOXL2) is one of the lysyl oxidases (LOX) families. At present, most of scholars consider that LOXL2 is a neoplasm metastasis gene, whereas some others believe that LOXL2 is a neoplasm suppressor gene. Studies found that LOXL2 gene combined with other oncogenes promotes neoplasm invasion, metastasis and indicates a poor prognosis. Related researches provide new ideas for judging tumor metastasis and prognosis and looking for new targets for cancer therapy.