%A WANG Wen-juan %T Roles of the liver regeneration phosphatase-3 and its inhibitors in tumor %0 Journal Article %D 2012 %J Journal of International Oncology %R %P 415-417 %V 39 %N 6 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_8799.shtml} %8 2012-06-08 %X Phosphatase of regenerating liver-3 (PRL-3) is a novel small molecule proteintyrosinephosphatase, which plays an important role in the oncogenesis and deveopment of tumors. Studies show that PRL-3 regulates neoplasm progress through participating in multiple signal pathways. Its high expression can significantly promote neoplasm metastasis in cancer tissue. However, there is no expression of PRL-3 in most normal tissue. PRL-3 is expected to be a potential tumor maker of diagnosis and a new target for the therapy of cancer.