%A ZHAO Da-hang %T Antitumor effect of inhibitor of growth 4 %0 Journal Article %D 2012 %J Journal of International Oncology %R %P 422-424 %V 39 %N 6 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_8801.shtml} %8 2012-06-08 %X Inhibitor of growth 4 (ING4) is an important member of anti-oncogene family. The expression of ING4 is significantly lower in many malignancies. ING4 involves in multiple processes, such as tumorigenesis, regulation of cell cycle, cell apoptosis, DNA repair and angiogenesis, which have a significant impact on the progression and prognosis of tumor. ING4 may serve as a promising prognostic maker as well as a potential therapeutic target for cancer.