%A XIE Xia %T Effect of cyclooxygenase-2 inhibitor in anti-leukemia %0 Journal Article %D 2012 %J Journal of International Oncology %R %P 462-464 %V 39 %N 6 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_8813.shtml} %8 2012-06-08 %X Cyclooxygenase-2 (COX-2) plays an important role in the development of leukemia. COX-2 inhibitor plays a certain antileukemia role in the process. Many studies show that COX-2 inhibitor plays antileukemia role by inhibiting the proliferation of leukemia cell, promoting apoptosis, affecting cell cycle, inhibiting cell metastasis and reversing cell drug resistance and so on. Therefore, the researches about the antileukemia mechanisms of COX-2 inhibitor will provide a new target in clinical prevention and treatment of leukemia.