%A WANG Meng, YANG Ji-Yuan %T EML4-ALK fusion gene in non-small cell lung cancer %0 Journal Article %D 2012 %J Journal of International Oncology %R %P 848-850 %V 39 %N 11 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_8928.shtml} %8 2012-11-08 %X EML4-ALK fusion oncogene represents a new molecular target which appears mainly in lung adenocarcinoma. EML4-ALK is detected more frequently in young non-small-cell lung cancer patients who never or light smoke. ALK inhibitors(crizotinib)for the treatment of the EML4-ALK-positive non-small cell lung cancer has a high response rate. This finding can improve the individual treatment of non-small cell lung cancer.