%A ZHANG Li-Na, YUE Wen-Tao %T Aldo-keto reductase superfamily and lung cancer %0 Journal Article %D 2013 %J Journal of International Oncology %R %P 43-46 %V 40 %N 1 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_8974.shtml} %8 2013-01-08 %X Aldehyde and ketone reductase (AKR) superfamily is NADPH-dependent oxidoreductase. As a rate-limiting enzyme in polyols metabolic pathway, the activation or inactivation of AKR involves in neoplastic process of lung cancer with the metabolism of environment toxic. AKR is related to drug resistance of chemotherapy, which will be the prognostic factor of lung cancer.