%A ZHANG Lei, XU Jian-Yu, XU Xiang-Ying %T Endostatin in the treatment of non-small-cell lung cancer %0 Journal Article %D 2013 %J Journal of International Oncology %R %P 50-53 %V 40 %N 1 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_8976.shtml} %8 2013-01-08 %X Endostatin is a novel anti-angiogenic drug which through multiple pathway inhibits vascular endothelial growth factor expression, to achieve the purpose of the inhibition of tumor angiogenesis. The drug in the treatment of non-small-cell lung cancer in pre-clinical study and clinical application show that: used alone have anti-tumor effect; combined with radiotherapy and chemotherapy can obtain short-term curative effect, and does not increase treatment related toxicity. The adverse effect of the drug is mild and can be well tolerated.