%A CAI Jing-Jing, MENG Qian-Li, GUO Hai-Ke %T Advances on heme oxygenase-1 on angiogenesis of tumors %0 Journal Article %D 2013 %J Journal of International Oncology %R %P 255-259 %V 40 %N 4 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9040.shtml} %8 2013-04-08 %X Studies show that heme oxygenase-1 (HO-1) can promote the tumor neovascularization via interacting with angiogenic factors, such as vascular endothelial growth factor (VEGF) and stromal cell-derived factor-1. On the other hand, HO-1 may suppress angiogenesis in tumors via inhibiting the transcription of NF-κB. In a word, HO-1 may participate in the pathophysiological process of tumor angiogenesis, and may be a new target for cancer treatment.