%A YANG Lu-Lu, LIU Xin %T Resistance mechanisms and the countermeasures of acute leukemia %0 Journal Article %D 2013 %J Journal of International Oncology %R %P 377-380 %V 40 %N 5 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9078.shtml} %8 2013-05-08 %X Acute leukemia ( AL) is a malignant disease of clonal hematopoietic stem cell abnormalities. Chemotherapy is the main method for the treatment of AL, but the chemotherapy drug resistance has become a major obstacle to successful treatment. There is often a series of drug cooccurrence of drug resistance, and that is multidrug resistance.