%A ZHOU Wei-Min, ZHONG Kuang-biao, GUI Ming %T Research about NNMT gene in cancer %0 Journal Article %D 2013 %J Journal of International Oncology %R %P 732-735 %V 40 %N 10 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9190.shtml} %8 2013-10-08 %X Nicotinamide N-methyltransferase ( NNMT) is a S-adenosyl-L-methionine ( SAM) dependent cytoplasm enzyme , which plays a vital rolein the biotransformation and detoxification of many drugs and xenobiotic compounds. Recent studies have revealed abnormal expression of NNMT in many tumors, which may contribute to tumorigenesis and tumor developmentand radiotherapy or chemotherapy resistance.