%A YAN Xue-Bing, ZHU Qing-Chao, JIN Zhi-Ming %T Y-box-binding protein 1 and epithelialmesenchymal transition %0 Journal Article %D 2013 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2013.12.005 %P 896-899 %V 40 %N 12 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9214.shtml} %8 2013-12-10 %X In the process of epithelialmesenchymal transition (EMT), cellcell adherence is disrupted, apicobasal polarity is lost, the ability of antiapoptosis, migration and invasion is acquired. Yboxbinding protein 1 (YB1) is a member of the coldshock protein superfamily, containing a structurally and functionally conserved cold shock domain. Studies indicate that YB1 can promote the occurrence and development of tumors by regulating EMT. In the process of EMT mediated by YB1, various transcription factors and signal pathways play important roles.