%A ZHU Hao, XU Jin-Fang, SHEN Hong %T Clinical trials of receptor protein tyrosine kinase inhabitors in malignant glioma %0 Journal Article %D 2013 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2013.11.010 %P 833-836 %V 40 %N 11 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9250.shtml} %8 2013-11-08 %X The occurrence and development of malignant glioma are closely related to abnormal overexpression and activation of receptor tyrosine kinase (RTK) signal transduction pathways. Targeted therapeutic drugs such as RTK inhibitors, RTK downstream signaling pathway inhibitors and multitarget inhibitors can targeting treat malignant glioma at molecular level, some of which have been investigated in clinical trials and achieved good therapeutic effects.