%A Tang Nailing, Guo Zhi, Yang Xueling %T Transforming growth factor-β and tumor %0 Journal Article %D 2015 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2015.01.011 %P 43-45 %V 42 %N 1 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9527.shtml} %8 2015-01-08 %X Many studies show that transforming growth factorβ (TGFβ) can suppress tumor by inhibiting proliferation and dedifferentiation of cells and promoting cell apoptosis at early stage. But during the progression of tumor, its tumorpromoting action will be more and more obvious with the variation of TGFβ itself and its signal path. TGFβ signal path inhibitors have antitumor activity, but the clinical effects and side effects still need to be observed.