%A YOU Yan-Jie, LI Wen-Mei, LIU Jia-Jia, YUAN Yi %T Cyclin-dependent kinase 10 and tumorigenesis %0 Journal Article %D 2014 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2014.11.004 %P 811-812 %V 41 %N 11 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9542.shtml} %8 2014-12-03 %X Cyclindependent kinase 10 (CDK10) function as a tumor suppressor gene through regulating cell cycle interacting with transcription factor Ets2. Studies demonstrate that the downregulation of CDK10 expression occurs in multiple cancer types, indicating a potential application of CDK10 as a molecular diagnostic marker as well as therapeutic target.