%A MA Dan-；Ma-Ling %T Research progress of ovarian cancer apoptosis related factor—Survivin and Smac %0 Journal Article %D 2015 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2015.04.020 %P 313-315 %V 42 %N 4 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9654.shtml} %8 2015-04-08 %X Survivin is the strongest member of the inhibitor of apoptosis protein (IAP) family. Smac is the second mitochondriaderived activator of cysteine proteases, which can promote apoptosis by combining with IAP. Abnormal expression of them is closely related with occurrence, development, treatment tolerance and prognosis of ovarian cancer. It is prompted that Survivin and Smac are expected to play important roles in the early diagnosis and targeted therapy of ovarian cancer.