%A Lian Yifan, Wang Keming %T Molecular mechanism of long non-coding RNAs in tumor drug resistance %0 Journal Article %D 2015 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2015.06.010 %P 439-441 %V 42 %N 6 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9666.shtml} %8 2015-06-08 %X Long non-coding RNAs (lncRNAs) are closely related to the tumorigenesis, proliferation, metastasis and clinical outcome, whihc play important roles in the process of drug resistance of many tumor cells. Recently, research indicates that many lncRNAs regulate drug resistance of tumor cells through a variety of signaling pathways both in vitro and in vivo. Furthermore, it is also found that after blocking the relevant targets can reverse this chemoresistance.