%A Wang Yan, Wang Lu, Feng Jiangzhou, Li Deng %T Research progress of CTHRC1 in gastrointestinal cancers %0 Journal Article %D 2016 %J Journal of International Oncology %R 10.3760/cma.j.issn.1673-422X.2016.05.016 %P 382-384 %V 43 %N 5 %U {https://gjzlx.sdfmu.edu.cn/CN/abstract/article_9961.shtml} %8 2016-05-08 %X Collagen triple helix repeat containing 1 (CTHRC1) can repair the injured vessel by limiting the deposition of collagen and promoting cell migration. CTHRC1 is mainly regulated by WntPCP signaling pathway， transforming growth factor (TGF)bone morphogenetic protein (BMP) signaling pathway and extracellular signalregulated kinase (ERK)matrix metalloproteinase 9 (MMP9) signaling pathway. Recent studies have identified that CTHRC1 is aberrantly expressed in gastrointestinal cancers and associated with the occurring and development of cancers.