优秀校友个人简介 |
史文娜，女，1982年06月出生，2007年毕业于betway必威登陆网址 （原泰山医学院）药学院制药工程专业，获得学士学位；2010年毕业于山东大学药学院临床药学专业，获得硕士学位；2017年毕业于首都医科大学基础医学院药理学专业，获得博士学位。现工作单位betway必威登陆网址 附属肿瘤医院，副主任药师。主要工作经历，2010年-2020年山东省肿瘤医院药学部临床药学负责人，主管药师；2021年-至今，betway必威登陆网址 附属肿瘤医院药学部质子中心负责人，副主任药师；2020.02-至今，山东大学和betway.com 联合培养，博士后。主要研究方向为抗肿瘤机制及抗感染耐药机制，为首国家发明专利1项，主持省部级科研课题4项，发表SCI论文十余篇，副主编及参编书籍5部。 附研究成果如下： ØWenna Shi,Zuozhong Chen, Xu Chen, Lili Cao, Ping Liu, Shujuan Sun*.The combination of minocycline and fluconazole causes synergistic growth inhibition against Candida albicans: an in vitro interaction of antifungal and antibacterial agents.FEMS Yeast Res.2010, 10(7). ØWenna Shi, Hui Li, Yuguo Liu, Xiang Zhang, and Shujuan Sun.The Effect of Fluconazole inCombination with Rifampin invitro on Candida albicansBiofilms.Anti-Infective Agent2013,11(2):136-143. ØA series of books on the main points of drug treatment for common diseases, Oncology,Deputy Editor-in-Chief, people's Health Publishing House (ISBN No.: 9787117199674), 2015, Beijing ØXinfeng Yu ; Ruilian Li;Wenna Shi; Tao Jiang; Yufei Wang; Cong Li; Xianjun Qu. Silencing of MicroRNA-21 confers the sensitivity to tamoxifen and fulvestrant by enhancing autophagic cell death through inhibition of thePI3K-AKT-mTOR pathway in breast cancer cells. Biomedicine & Pharmacotherapy 2015, 77: 37-44. ØWenna Shi, Shuxiang Cui,Zhiyu Song, Shuqing Wang,Shiyue Sun, Xinfeng Yu, YeLi, Yuhang Zhang, ZuhuaGao*, Xianjun Qu*.Overexpression of SphK2contributes to ATRA resistancein colon cancer through rapiddegradation of cytoplasmic RXRαby K48/K63-linkedpolyubiquitination. Oncotarget. 2017,8:39605-39617. ØChina invention patent, Antifungal composition and its use (patent no. ZL 2016 10343488.7), State intellectual property Office of China, Grant time September 4, 2018,The first place. ØXiaohui Tang, Haisheng Chen, Guanxuan Chen, Cunxian Duan, Qing Fan, Yanhong Wang, Zhijun Li,Wenna Shi*, Yuguo Liu*. Sphingosine 1-phosphate correlation with radiotherapy through qualitative determination by LC-MS/MS. Thoracic cancer.Thoracic Cancer ,2020, 116(6) ØHaisheng Chen, Hui Li, Cunxian Duan, Chuanjie Song, Zuoliang Peng, Hui Li,Wenna Shi*. Azoles resistance reversal by oridonin in Candida albicans. 2020, mycoses. Journal of Global Antimicrobial Resistance , 2021, 24: 296-302 . ØYuhang Zhang;Wenna Shi; Shuhua Wu; Rongrong Miao; Shiyue Sun; Dongdong Luo; Shengbiao Wan; Zhikun Guo; Wenyu Wang; Xinfeng Yu; Shuxiang Cui; Xianjun Qu. SphK2 confers 5-fluorouracil resistance to colorectal cancer via upregulatingH3K56ac-mediated DPD expression, Oncogene , 2020, 3929(29) ØWei Tian; Yinping Sun; Yuping Cheng; Xiao Ma; Weina Du;Wenna Shi*; Qisen Guo. Arsenic sulfide reverses cisplatin resistance in non-small cell lung cancer in vitro and in vivo through targeting PD-L1, Thoracic Cancer , 2021, 12(19): 2551-2563
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