姓名：张春雨
硕士生导师
职称：副教授
联系方式：zhangchunyu@sdfmu.edu.cn
研究方向：
1.铂类抗肿瘤药物开发及治疗应用;
2.基于金属团簇药物/探针的纳米生物效应研究;
3.基于先进光源的单细胞同步辐射成像分析。
主要学术任职：
1.担任Nano Today, Small, Molecular Pharmaceutics等期刊审稿人
主持科研课题：
1.国家博士后科学基金,面上项目, 2022M711974, 2022/06-2023/09, 8万元,已结题,主持;
2.betway必威登陆网址 青年科学基金培育资助计划项目,202201-003,2022/10-2024/10,10万元,在研,主持;
3.山东省医药卫生科技项目,青年项目, 202313030397, 2024/01-2025/12, 5万元,在研,主持;
4.betway必威登陆网址 高层次人才引进经费资助项目,2023/09-2028/08,100万,在研,主持。
近五年代表性论文（限第一作者和通讯作者）：
(1)Xu, C.; Xia, D.; Zhang, X.; Yao, Q.; Wang, Y.;*Zhang, C.,*In situ analysis of metallodrugs at the single-cell level based on synchrotron radiation technology.TrAC-Trends in Analytical Chemistry2024,171, 117515.
(2)Zhang, C.;*Zhang, N.; Niu, W.; Li, R.; Liu, Y.; Mu, Y.; Xu, C.;*Yao, Q.;*Gao, X.,*Ultrasmall platinum nanoclusters: A potent chemotherapeutic drug for cancer-specific DNA damage with optimizing therapeutic efficacy while minimizing systemic toxicity.Nano Today2024,55, 102195.
(3)Zhang, C.;#Zhang, K.;#Cui, Y.;#Guo, Y.; Wang, C.;Xu, C.;Yao, Q.;Zhao, Y.;Chen, C.;*Wang, Y.,*Multifunctional Nanoprobe for 3D Nanoresolution Imaging of Intact Cell HER2 Protein with Hard X-ray Tomography.Anal.Chem.2023,95,2129-2133.(Cover article)
(4)Zhang, C.;#Xu, C.;#Gao, X.;*Yao, Q.,*Platinum-based Drugs for Cancer Therapy and Anti-tumor Strategies.Theranostics2022,12, 2115-2132. (Highly Cited Paper)
(5)Zhang, C.; Yao, S.; Xu, C.; Chang, Y.; Zong, Y.; Zhang, K.; Zhang, X.; Zhang, L.; Chen, C.; Zhao, Y.; Jiang, H.;*Gao, X.;*Wang, Y.,*3D Imaging and Quantification of the Integrin at a Single-Cell Base on a Multisignal Nanoprobe and Synchrotron Radiation Soft X-ray Tomography Microscopy.Anal.Chem.2021,93, 1237-1241.
(6)Zhang, C.; Gao, L.;*Yuan, Q.; Zhao, L.; Niu, W.; Cai, P.; Li, J.; Han, X.; He, Z.; Gao, F.; Wang, Y.; Jiang, H.; Chai, Z.; Gao, X.,*Is GSH Chelated Pt Molecule Inactive in Anti-Cancer Treatment? A Case Study ofPt6GS4.Small2020,16, 2002044.
(7)He, Z.;#Ye, F.;#Zhang, C.;#Fan, J.;#Du, Z.; Zhao, W.; Yuan, Q.; Niu, W.; Gao, F.; He, B.; Cao, P.; Zhao, L.; Gao, X.; Gao, X.; Sun, B.; Dong, Y.; Zhao, J.; Qi, J.; Liang, X.; Jiang, H.;*Gong, Y.;*Tan, W.;*Gao, X.,*A Comparison of Remdesivir Versus Gold Cluster in COVID-19 Animal Model: A Better Therapeutic Outcome of Gold Cluster.Nano Today2022,44, 101468.(co-first author）
(8)Zhang, Y.;#Zhang, C.;#Xu, C.;*Wang, X.; Liu, C.; Waterhouse, G. I. N.; Wang, Y.;*Yin, H.,*Ultrasmall AuNanoclusters forBiomedical andBiosensingApplications: AMini-review.Talanta2019,200, 432-442.(co-first author）
