姓名：王延风
硕士生导师
职称：教授
联系方式：wangyanfeng@sdfmu.edu.cn
研究方向：
1. 基于荧光探针成像的生物活性研究
围绕与疾病相关的生物靶点，以小分子荧光探针成像为研究手段，进行基于靶点结构的生物活性研究。
2. 化学生物学研究
通过合理设计、合成、生物筛选、分离、富集等手段，获得能与氨基酸、蛋白、有机小分子、无机离子等靶物质特异性结合的探针。
主要学术任职：
青海省“高端创新人才千人计划”（引进拔尖人才）
主要获奖情况（包括作为指导教师）：
1. 2021年度betway必威登陆网址 “十大重要科研进展”
2. 研究生中三人次获得“国家奖学金”；
3. 研究生中两人次获得“于金明科技创新基金”；
4. 研究生中两人次的毕业论文被评为“山东省优秀硕士学位论文”；
5. 研究生中一人次获得“山东省优秀硕士毕业生”称号；
主持科研课题：
1. 国家自然科学基金青年项目.，2014-2016年，25万元，已结题，主持；
2. 海西州科技计划项目.，2017.01-2019.12，30万元，已结题，主持；
3. 海西州科技计划项目.，2022.10-2024.10.，30万元，在研，主持；
4. 横向课题：Trifarotene中间体工艺开发及合成.，32万元，在研，主持；
5. 横向课题：小分子化合物类传感器的合成.，8万元，在研，主持。
近五年代表性论文（限第一作者和通讯作者）：
1.Yuanyuan Liu, Chengying Zhang, Yongchun Wei, Huimin Chen, Lingxiu Kong, Qixin Chen*,Yanfeng Wang*. De Novo-Designed landmine warfare strategy luminophore for super-resolution imaging reveal ONOO– evolution in living cells.Chemical Engineering Journal.2021. 422,130151.
2.Yongchun Wei, Lingxiu Kong, Huimin Chen, Yuanyuan Liu, Yifei Xu, Han Wang, Guiqian Fang, Xintian Shao, Fei Liu,Yanfeng Wang*, Qixin Chen*.Super-resolution image-based tracking of drug distribution in mitochondria of a label-free naturally derived drug molecules.Chemical Engineering Journal. 2022. 429，
3.Yongchun Wei, Yuanyuan Liu, Yongqi Heb andYanfeng Wang*. Mitochondria and lysosome-targetable fluorescent probes for hydrogen peroxide.Journal of Materials Chemistry B.2021, 9, 908–920.
4.Lingxiu Kong, Chunpeng Jiao, Lingyu Luan, Sheng Li, Xia Ma,Yanfeng Wang*. Reversible Ni2+fluorescent probe based on ICT mechanism and its application in bio-imaging of Zebrafish.Journal of Photochemistry & Photobiology, A: Chemistry. 2022，422,113555
5.Jiarao Sun, Xiaoli Cao, Wenjuan Lu, Yongchun Wei, Lingxiu Kong, Wei Chen, Xintian Shao,Yanfeng Wang*., Recent advances in fluorescent probes of peroxynitrite: Structural, strategies and biological applications,Theranostics,2023; 13(6): 1730-1758.
6.Chunpeng Jiao, Yuanyuan Liua, Jingxiang Pang, Wenjuan Lu, Pingping Zhang,Yanfeng Wang*. A simple lysosome-targeted probe for detection of hypochlorous acid in living cells.Journal of Photochemistry & Photobiology A: Chemistry. 392 (2020) 112399.
7.Yuanyuan Liu, Chunpeng Jiao, Yongchun Wei, Wenjuan Lu, Pingping Zhang,Yanfeng Wang*. A highly specific rhodamine B based turn-on fluorescent probe for nitric oxide and application in living cells.Tetrahedron.76 (2020) 131622.
8. Chunpeng Jiao, Yuanyuan Liu, Wenjuan Lu, Pingping Zhang, Xia Ma andYanfeng Wang*. A simple sensor based on 1,8-naphthalimide with large Stokes shift for detection of hypochlorous acid in living cells.RSC Advances. 2019, 9, 31196–31201.
9. Yuanyuan Liu, Chunpeng Jiao, Wenjuan Lu, Pingping Zhang andYanfeng Wang *. Research progress in the development of organic small molecule fluorescent probes for detecting H2O2.RSC Advances. 2019, 9, 18027.
10. 矫春鹏, 刘媛媛, 路文娟, 张平平,王延风*. 检测活性氮/活性氧的分子荧光探针. 有机化学. 2019, 39, 591-616.
11. A “weak acid and weak base” type fluorescent probe for sensing pH: mechanism and application in living cells. RSC Advances. Chunpeng Jiao, Jingxiang Pang, Li Shen,* Wenjuan Lu, Pingping Zhang, Yuanyuan Liu, Jing Li, Xianhui Jia andYanfeng Wang *. 2019, 9, 20982.
12. Lingxiu Kong, Wenjuan Lu, Xiaoli Cao, Yongchun Wei, Jiarao Sun andYanfeng Wang *. The design strategies and biological applications of probes for the gaseous signaling molecule hydrogen sulfide.Journal of Materials Chemistry B.2022, 10, 7924–7954.
