Objective: To investigate the clinical value of arthroscope-assisted ankle arthrodesis in the treatment of traumatic arthritis of foot and ankle. Methods: From February 2017 to May 2019, retrospective analysis of the 43 cases of the clinical data of patients with severe traumatic ankle arthritis was made, 23 cases of ankle arthrodesis was performed arthroscopically (minimally invasive group), 20 patients who underwent open ankle arthrodesis (open group), and postoperative pain score difference of the day and 7 days, and osseous fusion rate after 6 months and 1 year and the differences between the AOFAS ankle function score were compared two groups of patients. Results: The pain scores of the minimally invasive group were (4.18±1.10) and (1.55±0.52) 1 and 7 days after surgery, which were both lower than those of the open group(5.54±1.15)and(3.45±0.58).The differences were statistically significant ( t=-3.959,-11.327, P<0.001). The bone fusion rate of the minimally invasive group was 82.61% 6 months after surgery, which was significantly higher than that of the open group(35.00%).The difference was statistically significant ( χ ²=10.143, P＜0.001). Bone fusion was formed in both groups at 1 year after surgery. Six months after surgery, there was no difference in AOFAS ankle function score between the two groups ( P>0.05).AOFAS score was (77.55±5.70) in the minimally invasive group and (66.49±4.55) in the open group 1 year after surgery, and the difference between the two groups was statistically significant( t=6.977, P<0.001). Conclusion: Minimally invasive ankle arthrodesis has more advantages in the treatment of severe traumatic arthritis of foot and ankle, which can reduce postoperative pain, improve the rate of early bone fusion and accelerate the recovery of foot and ankle function, which is worthy of further basic and clinical studies.