国际肿瘤学杂志

国际肿瘤学杂志››2011,Vol. 38››Issue (10): 790-793.

• 综述 •上一篇下一篇

微小RNA在卵巢癌中的作用

张春洁, 李娜, 金平

  1. 730000兰州 兰州大学第一临床医学院妇产科学
  • 出版日期:2011-10-08发布日期:2011-09-27
  • 通讯作者:金平，E-mail：pingjin66@sina.com E-mail:pingjin66@sina.com

Function of microRNAs in ovarian cancer

ZHANG Chun-Jie, LI Na, JIN Ping

  1. First Clinical Medical School , Lanzhou University , Lanzhou 730000, China
  • Online:2011-10-08Published:2011-09-27
  • Contact:Corresponding author: JIN Ping, E-mail: pingjin66@sina.com E-mail:pingjin66@sina.com

PDF

1773

被引次数

6

摘要：微小RNA(miRNA)在卵巢癌中表达明显改变。基于微阵列芯片检测的卵巢癌相关miRNA表达谱和后续的对个别miRNA的深入研究，发现其与卵巢癌的发生、发展、复发、耐药等密切相关，有望用于卵巢癌早期诊断、复发检测、预后判定及治疗。

Abstract:The expression of microRNAs (miRNAs) alters obviously in ovarian cancer. Through miRNA profile based on a microarray platform and further research on individual one, they are found to be closely related to pathogenesis, progression, recurrence, and drug resistance of ovarian cancer and have a good prospect inapplying itin the early diagnosis, detection recurrence, prognosis andtherapy ofovarian cancer.